The Safety of High Dose Labetalol in the Pregnant Population
Por um escritor misterioso
Descrição
Hypertension in pregnancy is one of the leading causes of maternal mortality and rapid treatment is critical. Treatment of emergent hypertensive crises in pregnancy is limited to only three medications, one of which is labetalol. Current literature recommends a daily maximum intravenous labetalol dose of 300 mg per day. However, this maximum dose has not been studied in pregnancy where higher doses may be required.
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These highlights do not include all the information needed to use LABETALOL HYDROCHLORIDE INJECTION safely and effectively. See full prescribing information for LABETALOL HYDROCHLORIDE. LABETALOL HYDROCHLORIDE IN SODIUM CHLORIDE injection , for
Oral antihypertensive regimens (nifedipine retard, labetalol, and methyldopa) for management of severe hypertension in pregnancy: an open-label, randomised controlled trial - The Lancet
Pharmaceutics, Free Full-Text
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PDF) Safety and efficacy of methyldopa and labetalol in controlling blood pressure in hypertensive disorders of pregnancy
Frontiers Pregnancy-Related Hormones Increase UGT1A1-Mediated Labetalol Metabolism in Human Hepatocytes
The Safety of High Dose Labetalol in the Pregnant Population
Pharmacokinetics of the most commonly used antihypertensive drugs throughout pregnancy methyldopa, labetalol, and nifedipine: a systematic review
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